International Research Conference
Homeopathy – Groundbreaking Science and Global Health
Evolving evidence: an overview of the latest findings in homeopathy research
Friday, October 17 / 1:45 PM – 2:30 PM
Speaker: Rachel Roberts, FSHom, FFHom (Hon)
Presentation focus:
Homeopathy is a controversial topic, with polarised opinions as to whether valid evidence to support the effectiveness of this treatment modality does, or does not exist.
An objective overview of the current status of the clinical evidence base for homeopathy provides valuable insights into what data actually exists on this topic, enabling us to look beyond the hyperbole often generated by individuals on both sides of the debate.
Findings from a range of key studies will be considered, from large-scale observational studies to highly influential systematic reviews and meta-analyses of randomised controlled trials (RCTs), showing how the evidence base for homeopathy has evolved over the past 15 years.
The strengths and weaknesses of the evidence base for homeopathy will be assessed, as well as the factors which have determined the shifts seen in the evidence base from ~2010 to 2025.
This dual approach aims to provide a clearer understanding of the current status of the evidence, which in turn directly informs strategies for future research in this field. In particular, the data shared will illustrate the need for further targeted research, aimed at building on the existing promising findings from multiple clinical studies which demonstrate that homeopathy may have beneficial effects in patients with common clinical conditions.
Keywords: Homeopathy; clinical research; trial design; methodology
Homeopathic Treatment as an Add-On Therapy May Improve Quality of Life and Prolong Survival in Patients with Non-Small Cell Lung Cancer: A Prospective, Randomized, Placebo-Controlled, Double-Blind, Three-Arm, Multicenter Study and related studies
Friday, October 17 / 2:50 PM – 3:35 PM
Speaker: Michael Frass, MD
Presentation focus: Patients with advanced non-small cell lung cancer (NSCLC) have limited treatment options. Alongside conventional anticancer treatment, additive homeopathy might help to alleviate side effects of conventional therapy. We wanted to investigate the effect of additive homeopathy on quality of life (QoL) and survival in NSCLC patients.
Methods. In this prospective, randomized, placebo-controlled, double-blind, three-arm, multicenter, phase III study, we compared additive homeopathic treatment and placebo in NSCLC stage IV patients with respect to QoL in the two randomized groups and survival time in all three groups. Treated patients visited the outpatients’ centers every 9 weeks. 150 Patients with stage IV NSCLC were included in the study. 98 received either individualized homeopathic medicinal products (n=51) or placebo (n=47) in a double-blinded fashion. 52 control patients (third group) without any homeopathic treatment were observed for survival only.
Results. QoL as well as functional and symptom scales showed significant improvement with homeopathy when compared to placebo after 9 and 18 weeks of homeopathic treatment (p<0.001). Median survival time was significantly longer in the homeopathy group (435 days) vs placebo (257 days; p=0.010) as well as vs control (228 days; p<0.001). Survival rate in the homeopathy group differed significantly from placebo (p=0.020) and from control (p<0.001).
Conclusion. QoL improved significantly with homeopathy group compared to placebo. In addition, survival was significantly longer in the homeopathy group versus placebo and control. A higher QoL might have contributed to the prolonged survival. The study suggests that homeopathy positively influences not only QoL but also survival. Further studies including other tumor entities are warranted. The paper confirms results of a previous open pragmatic study regarding QoL, as well as a retrospective study regarding prolonged survival. The interval of 9 weeks between appointments is compatible with the financial resources of the public health services as well as with the time resources of the patients. Therefore, we believe that additive homeopathy fits perfectly into the health program of public health services.
Overview and quality assessment of health economic evaluations for homeopathic therapy: an updated systematic review – Expert Rev Pharmacoecon Outcomes Res. 2023 Oct 5:1-26.
Friday, October 17 / 3:35 PM – 4:20 PM
Speaker: Michelle Dossett MD, Ph.D.
Presentation focus: This presentation will review a health economic evaluation examining health outcomes and costs associated with homeopathic therapy published by Thomas Ostermann and colleagues in 2024. Their systematic review examined 21 studies conducted between 1993 and 2021 covering a variety of different health conditions. The majority of studies found that homeopathic therapy was at least equally effective for a reduced or similar cost compared to the control. While there was a trend toward higher-quality research over time, the quality of the majority of studies was moderate or poor, limiting overall conclusions about the cost-effectiveness of homeopathic therapy.
Whole system bioassays in homeopathic basic research: state of research.
Friday, October 17 / 4:20 PM – 4:50 PM
Speaker: Stephan Baumgartner Ph.D.
Presentation focus: Whole plant bioassays in homeopathic research combine several advantages. It is possible to analyze large numbers of individual organisms in their response to homeopathic treatments without ethical concerns. Repetitive series of experiments and multicenter trials with identical materials are easily feasible, as well as full implementation of systematic negative control experiments to document test system stability. Furthermore, plants are deeply connected to their environment what allows studying regulative reactions of whole systems in still comparably simple models. Repeated experiments demonstrated specific biological effects of even highly diluted homeopathic remedies. The factors identified so far that modulate the response to homeopathic treatments provide evidence for specific states of complex systems responsible for reactivity to homeopathic preparations.
Integrating Homoeopathy: A Perspective within WHO’s Framework for Traditional Medicine.
Friday, October 17 / 4:50 PM – 5:35 PM
Speaker: Raj Manchanda, MD
Presentation focus: The World Health Organization (WHO) recognizes traditional medicine as an integral component of global healthcare. The WHO Global Traditional Medicine Strategy (2025–2034) aims to ensure universal access to safe, effective, and people-centered traditional, complementary, and integrative medicine (TCIM) to enhance public health and well-being. Structured around nine guiding principles, four strategic objectives, and eight key directions, the strategy outlines specific actions for Member States, WHO, and stakeholders to facilitate effective implementation.[1]
Homeopathy, acknowledged as part of TCIM in nearly 100 countries, maintains its relevance across diverse healthcare systems. [2] However, its sustained integration requires alignment with scientific scrutiny, regulatory frameworks, and evolving societal expectations while reinforcing evidence-based practices to enhance personalized, patient-centered care within public health.
Stakeholders—including practitioners, researchers, industry leaders, educational institutions, professional bodies, and civil society organizations—are instrumental in strengthening homeopathy’s global position. Professional technical organizations such as the Liga Medicorum Homoeopathica Internationalis (LMHI), present in over 70 countries, and the American Institute of Homeopathy, with a legacy exceeding a century, have witnessed the evolution of homeopathy worldwide.
Aligned with the WHO TM Strategy and supported by friendly Member States like India, South Africa, and Latin American nations, these organizations can drive global advancements in homeopathy. Recognizing the need for structured action, a ten-year plan is essential to revive, sustain, and expand homeopathy within TCIM. This plan must be region or country specific, addressing historical, cultural, and systemic contexts to overcome unique challenges. An outline of this roadmap will be presented, providing a strategic framework for coordinated efforts to integrate homeopathy into global healthcare systems.
Notes
- 2025. Draft global traditional medicine strategy (2025–2034). Available at: https://apps.who.int/gb/ebwha/pdf_files/WHA78/A78_4Add1-en.pdf [accessed on 15 June 2025]
- 2019. WHO global report on traditional and complementary medicine 2019. Available at: https://www.who.int/publications/i/item/978924151536 [accessed on 15 June 2025]
Targeting the current gaps in homeopathy research – Cohort, Observational, and Case Series studies: Chronic case analyses from the Research Office of HOHM Foundation
Friday, October 17 / 5:35 PM – 6:20 PM
Speaker: Alastair Gray PhD HOHM Foundation
Presentation focus: Targeting the current gaps in homeopathy research – real-world, pragmatic, cohort, observational, economic, practice-based, practice generated and technology studies: Examples of research output from the research office at the Institute for the Advancement of Homeopathy / HOHM Foundation.
The conventional evidence hierarchy, with its systematic review and RCT’s at its apex, has long served as the gold standard in biomedical research. This model, for all of its benefits, presents inherent limitations when applied to complex, individualized therapies such as homeopathic medicine. Uncompromising commitment to the core principles of homeopathy—similars, individualization, symptom totality, and the dynamic patient response over time – in relationship to robust research, has resulted in the undervaluing of clinically meaningful outcomes observed in real-world practice.
This presentation firstly highlights key research gaps, including the underrepresentation of long-term cohort and observational designs, pragmatic trials, technology and economic studies as well as case series, that can better capture the nuanced effects of homeopathic management – and are often overlooked by current researchers in the field of homeopathic medicine, and reflect the patient-centered changes that are central to the process of healing in homeopathy, such as shifts in general well-being, emotional resilience, and chronic health improvement.
To address these gaps, the research office at the Institute for the Advancement of Homeopathy continues to ask relevant health services research (HSR) , and public health (PH) research questions and explore simple, low-hanging research pathways: (1) the development of mixed-methods studies incorporating both qualitative and quantitative outcomes to better reflect individual trajectories of change; (2) systematic documentation of high-quality case reports and case series using rigorous guidelines; (3) application of innovative research methods to assess homeopathy’s role in integrative care models; (4) the use of real-world evidence platforms and patient datasets to track longitudinal outcomes; and (5) continuing to focus on real world application of digital technologies at the client – patient interface with the focus on outcomes.
By broadening the methodological landscape, researchers can better evaluate homeopathy on its own epistemological terms, offering a more inclusive and clinically relevant evidence base. This reframing, championed by the IAH, is essential not only for academic rigor but also for informing future policy, education, clinical training, quality healthcare delivery and patient choice in integrative healthcare.
Efficacy of homoeopathic treatment: Systematic review of meta-analyses of randomised placebo-controlled homoeopathy trials for any indication
Saturday, October 18 / 9:00 AM – 9:45 AM
Speaker: Alastair Gray PhD HOHM Foundation
Presentation focus: Since 1997, several meta-analyses (MAs) of placebo-controlled randomised efficacy trials of homoeopathy for any indication (PRETHAIs) have been published with different methods, results and conclusions. To date, a formal assessment of these MAs has not been performed. The main objective of this systematic review of MAs of PRETHAIs was to evaluate the efficacy of homoeopathic treatment.
Methods
The inclusion criteria were as follows: MAs of PRETHAIs in humans; all ages, countries, settings, publication languages; and MAs published from 1 Jan. 1990 to 30 Apr. 2023. The exclusion criteria were as follows: systematic reviews without MAs; MAs restricted to age or gender groups, specific indications, or specific homoeopathic treatments; and MAs that did not assess efficacy. We searched 8 electronic databases up to 14 Dec. 2020, with an update search in 6 databases up to 30 April 2023.
The primary outcome was the effect estimate for all included trials in each MA and after restricting the sample to trials with high methodological quality, according to predefined criteria. The risk of bias for each MA was assessed by the ROBIS (Risk Of Bias In Systematic reviews) tool. The quality of evidence was assessed by the GRADE framework. Statistical analyses were performed to determine the proportion of MAs showing a significant positive effect of homoeopathy vs. no significant difference.
Results
Six MAs were included, covering individualised homoeopathy (I-HOM, n = 2), nonindividualised homoeopathy (NI-HOM, n = 1) and all homoeopathy types (ALL-HOM = I-HOM + NI-HOM, n = 3). The MAs comprised between 16 and 110 trials, and the included trials were published from 1943–2014. The median trial sample size ranged from 45 to 97 patients. The risk of bias (low/unclear/high) was rated as low for three MAs and high for three MAs.
Effect estimates for all trials in each MA showed a significant positive effect of homoeopathy compared to placebo (5 of 5 MAs, no data in 1 MA). Sensitivity analyses with sample restriction to high-quality trials were available from 4 MAs; the effect remained significant in 3 of the MAs (2 MAs assessed ALL-HOM, 1 MA assessed I-HOM) and was no longer significant in 1 MA (which assessed NI-HOM).
Discussion
The quality of evidence for positive effects of homoeopathy beyond placebo (high/moderate/low/very low) was high for I-HOM and moderate for ALL-HOM and NI-HOM. There was no support for the alternative hypothesis of no outcome difference between homoeopathy and placebo. The available MAs of PRETHAIs reveal significant positive effects of homoeopathy beyond placebo. This is in accordance with laboratory experiments showing partially replicable effects of homoeopathically potentised preparations in physico-chemical, in vitro, plant-based and animal-based test systems.
Addressing Antimicrobial Resistance: The Potential Role of Homeopathy
Saturday, October 18 / 9:45 AM – 10:30 AM
Speaker: Esther van der Werf, Ph.D.
Presentation focus: AMR poses a significant threat to global health, with more than 700,000 yearly deaths worldwide, expected to rise to 10 million within 30 years. There is an urgent need to decrease the use of antibiotics, and Primary care and agriculture are top targets for antimicrobial stewardship. Global, regional, and national strategies were developed in the last decade to reduce AMR. However, little progress has been made despite all significant efforts to reduce antibiotic use and AMR.
Given the magnitude of the problem, the insufficient strategies to reduce antimicrobial use and the urgency and impact of AMR, there is a need for novel strategies. Traditional, Complementary and Integrative Medicine (TCIM) may provide strategies and solutions that contribute to reducing (inappropriate) antibiotic use, specifically as part of a delayed prescription strategy or as an alternative/ add-on prevention or treatment strategy in both human and veterinary medicine. Homeopathy is one of the most popular TCIM strategies widely used worldwide.
The use of homeopathy in the prevention and treatment of infections is based on increasing scientific studies and evidence. To illustrate the substantial role homeopathy could play in helping to reduce the problem of AMR an overview of high-quality studies, including Systematic Reviews and Meta-analysis, Double-Blind Placebo-Controlled Randomised Clinical Trials (RCT) and Real-World Evidence (RWE) studies will be presented. In addition, HRI’s research programme on homeopathy and antimicrobial resistance (ENHANCE), which, to date, includes three systematic reviews and meta-analysis (Otitis Media, Tonsilitis and Sinusitis) and studies on the determination and validation of Core Outcome Sets (COS) for future primary care infection research (Acute Otitis Media and Sinusitis) will be introduced. This initiative, through a combination of high-quality research, interdisciplinary collaboration, and standardised methodologies, will strengthen the evidence assessing homeopathic treatment for primary care infections, ensuring safe and effective treatment alternatives for patients and thus contributing to the long-term goal of reducing antibiotic dependence.
Knee and hip pain study, “Individualised homoeopathic medicine versus placebo in the pain management of knee and hip osteoarthritis: A double-blind, randomised controlled trial.”
Saturday, October 18 / 11:00 AM – 11:45 AM
Speaker: Dr. Abhijeet Chakma, MD (Hom), RBTS
Presentation focus: Osteoarthritis is a progressive, degenerative disease affecting large weight-bearing joints. It is characterized by the loss of articular cartilage, diminished joint space, hypertrophy of the margins of bone with sub-chrondral sclerosis, and biochemical and morphological changes of the synovial membrane and joint capsule. The severity of symptoms varies among individuals; whereas pain and stiffness are the most troublesome complaints. Clinical symptoms of osteoarthritis are much significant for diagnosis and it can be established using the standards American College Rheumatology guidelines. Different investigation such as MRI, X-ray etc. are helpful for diagnosis of OA. Homoeopathic medicines have the potential to manage the pain episodes.
Objective: To assess the effect of Individualized homoeopathic medicine in managing the pain of knee and hip osteoarthritis.
Methods: A prospective, double blind, randomized (1:1), placebo controlled trial was conducted on 60 individuals suffering from osteoarthritis at R.B.T.S. Govt. Homoeopathic Medical College and Hospital, Muzaffarpur, Bihar, India from May, 2021 to February 2022. Due to limited evidence on the effectiveness of individualized homeopathic medicines (IHM) in knee and hip osteoarthritis, formal sample size calculation could not be done. We planned to achieve a target sample of 60 patients (30 in each group) within the stipulated time (α= 0.05 and power 80%). Taking into account for a maximum of 20% drop outs, total sample size required was 72. Patients aged between 35-80 years, of both sexes, of all socio-economic strata, clinically diagnosed cases of OA as per American College of Rheumatology criteria, self-reported or pre-diagnosed cases of OA and willing to participate in the study were included. Visual Analogue Scale (VAS) for pain (Score-A-1), stiffness (Score-A-2), loss of function (Score-A-3) were the primary outcomes and Osteoarthritis Knee & Hip Quality Of Life (OKHQOL) scale (Score-B) was the secondary outcome in this study. Both outcomes were measured at baseline and after 3 months. Comparative analysis was done to detect group differences. Intra and inter group analysis was done by paired and unpaired-t-test respectively.
Results: Statistically significant result was observed in both Intra and Inter group outcomes (p<0.05, at 95% CI). Group differences in score-A-1 (Mean difference: -5.83, 95% CI -6.71 to -4.94, p<0.001), in Score-A-2 (Mean difference: -5.43, 95% CI -6.38 to -4.48, p<0.001), in Score-A-3 (Mean difference: -5.60, 95% CI -6.50 to -4.69, p<0.001) and in Score-B (Mean difference: -106.87, 95% CI -142.77 to -70.96, p<0.001) were statistically significant after 3 months. However, the improvements were much better in Individualized Homoeopathic Medicine (IHM) group than placebo group. The frequently indicated medicines were Rhus toxicodendron, Medorrhinum, Bryonia and Syphilinum.
Conclusion: In this randomized placebo controlled study, it is observed that individualized homoeopathic medicine has beneficial effects in managing the pain of Knee and Hip OA and also improving the quality of life. Improvement in the control group was also significant but less than experimental group.
When Nothing Else Works: Case Studies of Cerebellar Ataxia and Parathyroid Carcinoma with Intractable Pain
Saturday, October 18 / 1:45 PM – 2:30 PM
Speaker: Dr. Juan Carlos Gamba, MD Presentation focus: This presentation explores the role of classical homeopathy in managing chronic intractable pain—musculoskeletal, neuropathic, oncologic, and beyond. Through selected clinical cases, I will show how individualized homeopathic treatment alone brought lasting relief and restored quality of life in patients for whom conventional medicine had failed. These outcomes highlight homeopathy’s potential to offer both healing and renewed hope.A review of basic science research in homeopathy. Part I
Saturday, October 18 / 2:30 PM – 3:15 PM
The theories and models of homeopathy: what do we know?
Speaker: Alex Tournier Ph.D.
Presentation focus: There is currently no generally accepted theory able to explain the observed clinical efficacy of homeopathy. We present our scoping review which aims to identify all theoretical approaches that have been used to explain homeopathy, with the objective of helping future theory elaboration and experimentation.
Methods: Medline, Embase, Scopus, Web of Science, PhilPapers, several online library catalogues, and personal libraries were searched for original studies up to 12th July 2024. The theories identified in this review were grouped into fourteen overarching theoretical frameworks.
Results: 2118 records were screened, 500 full texts were assessed for eligibility, and 216 studies were included in this review. Starting in 1832 until the late 20th century, only sporadic contributions were found. From the 1990s, a marked increase in scholarly output was recorded. The frameworks with the highest number of contributions were Humanities, Complex Systems, Water Structures, and Weak Quantum Theory. 22% of included publications described theoretical approaches that tried to cover both main aspects of homeopathy, 46% only Potentisation, 20% only the Principle of Similars (and 11% were unspecific).
Conclusions: This scoping review offers an overview of theories and models on the mode of action of homeopathy. Unexpectedly, the placebo did not emerge as such a framework.
The electrical, magnetic and photonic properties of homeopathic potencies
Speaker: Steven Cartwright Ph.D.
Presentation focus: Studies on homeopathic potencies using solvatochromic dyes have provided results that indicate remedies both produce an electrical field, and are stabilised and enhanced by applied static magnetic fields, whilst being negated by the application of an electric current.
Aims and Methods: Guided by these studies, parallel investigations have been conducted with an ultra-sensitive, extended range luminometer capable of detecting low level photon emissions and separately, ferric oxide nanoparticles of an average size of 10nm have been used to detect changes in ambient magnetic fields associated with potencies. Throughout the above investigations potencies of Arsenicum album have largely been used in order to be able to draw direct comparisons between the results of different investigative methods, supplemented with potencies of other remedies as required.
Results: Weak photon emissions in the UV and visible regions of the electro-magnetic spectrum have been detected from a range of potencies of Arsenicum album on application of an electric current. In addition, ferric oxide nanoparticles show changes in their spectra in the presence of potencies of Arsenicum album consistent with a weak magnetic field.
Discussion and Conclusions: The results obtained using luminometry and with ferric oxide nano particles complement and extend results already obtained using solvatochromic dyes. The range of data now available from these studies shows how the electrical, magnetic and photonic properties of potencies might interact and be common expressions of an underlying dynamic structure.
Keywords: Solvatochromic, Luminometer, Electrical, Photons, Magnetic
The science behind Homeopathy – An Overview
Speaker: Biplab Kumar Paul, Ph.D.
S. Bhandary, D. S. Bhar, A. Mondal, S. Manna, A. Singha, T. Maity, P.Sultana, D. Roy, N. Bala, P.Thakur, B. K. Paul*, A. Dey, C. Mahata, S. K. Das, R. Basu, D. Bera, M. Chakraborti, S. Kar, D. Ghosh. S. Manchanda, A. Khuran, S. Kar, P. Bandyopadhyay, T. Bhattacharyya, B. Choudhury, B. K. Choudhury, N.C. Sukul and P. Nandy1
1 The Centre for Interdisciplinary Research and Education, Kolkata
*University of Engineering and Management, Kolkata
Presentation focus: Homeopathic medicines, despite skepticism and challenges have persisted over 200 years, with recent research bringing them into the scientific fold. Ultra low dosages of drugs where the presence of original molecules is improbable has shown some significant benefits. This has prompted renewed interest in exploring the physiochemical nature and mechanism of such dilutions in biomedical and healthcare applications.
The medicinal property is obtained by serial dilution of the mother tinctures derived from inorganic /organic/ nosodes substances , chosen from the principle of “ similia similibus” or” like cures like” . It is diluted in water or in alcohol and then followed by vigorous shaking. two together being known as potentisation, giving rise to nanoparticles.
The decrease in size of the drug associate (Y) with an increase in potency (X) bears an empirical relation
Y= a X -n
where a and n are characteristic of each drug.
Dilution and succussion, are the two most important basic technology to prepare homeopathic medicines. First is law of similar ( the likes behave as likes- the material is chosen for the selection of the mother tincture) and the serial dilution in water or in ethanol, followed by mechanical vibration, The two together, known as potentisation. Potentisation dissociates the structure of medicine to nanoparticle and it forms coherent domains (CD) in the liquid, trapping energy from ambient electromagnetic field.
CD has long life as it cannot release the trapped energy by thermal radiation. But it can do so through guest molecules(present in the form of impurity or deliberately added solute material, the medicine)
The succussion dissociates the structure of medicine(2019, MedCrave IJ Complementary & Alternative Medicine 12(6), 221-223 )
Using some metal derived homeopathic medicines, it has been shown that when they are embedded in electroactive polymers, the conductivity and dielectric constant increase by several orders of magnitude ,making them a useful candidate for electronic industry (2017 , Homeopathy 102(4) 262-267)
According to QED, the water molecules can stay in the coherent domain (CD) or as individual water molecules. In presence of environmental electromagnetic field, the domains oscillate, giving rise to an extended coherence domain- a dissipative structure(DS). The succussed serial dilution in proper solvent carries the information about the solute via DS.
Change of structure of the medicine and its environment have been studied by different physical methods : NMR, DLS, AFM, Raman spectroscopy , Anomalous Dielectric Dispersion Detector and other studies.
One important part is that quantum particles are the ultimate constituents of all living and non-living objects. These energy states are represented by wave functions (WF). Following the principle of Quantum Entanglement (QE), any two or more particles may be linked up in a certain way, and become entangled or coherently coupled for a long time.
Following are the specialities of homeopathic medicines. The research works demonstrating the science behind homeopathy have been carried out in different laboratories and are summarised here.
References:
- Homeopathic medicines are nanoparticles (2021, Ed. M.A. Farrukh Pub: Intechopen Ltd, London)
- Different potencies of the nanomedicine CuM has an effect on membrane fluidity ( 2014 Am, J. Hom. Med 107(4)161-169)
- Assigning shelf life for homeopathic drug is an important issue from the user’s point of view. ( 2019, Homeopathy 108(4) 232-239).
- The drug can be used in electronic industry where their incorporation enhances the dielectric constant of polymers and hence modifies the electronic properties (2017 , Homeopathy 102(4) 262-267)
- These materials has an effect on germination of plant seeds. It invigorates and enhances root growth of bean seeds (2015 Int .J. Innov Research in Science and Engineering 3(3),74-78)
- Synthesis and characterization of Cu/Ag nanoparticle loaded mullite nanocomposite system is a potential candidate for antimicrobial and therapeutic application (2014 Biochem Biophys Acta 1840, 3264-3276)
- Electrical energy has been extracted from alcohol and bi-distilled water. separated by a platinum foil- a QED effect (2017, Energy Education Sc and Tech Part A: Energy Science and Research 35(3) 285-290)
- FTIR shows the variation in free and bound water molecules in different homeopathic potencies, (2014 Int. J. High dilution research 13(49)189:196)
- Cuprum metallicum potentised through both serial dilution and succussion in comparison to succussion alone on E.coli bacterial system and electrical properties of PVDF polymer shows the effect (2019 Ind. J. Research in Homeopathy 13(4) 209-213)
- Novel inclusion of engineered nanoparticles in horticultural sectors (2020 Horticulture International Journal 4(4) 12 5-1 27). 1-4)
- Nanoparticle and domain formation aspects of homeopathic medicine in electronic industry and power generation has been applied (2021 Academic Lettes ://doi.org/ 10820935/AL2462)
- Quantum entanglement theory – In recent time application of Quantum Entanglement theory has been used to explain the healing mechanism of highly diluted homeopathic medicine (2025, Ind. J.Research in Homeopathy, 19, 3-14)
A review of basic science research in homeopathy. Part II
Saturday, October 18 / 3:15 PM – 4:00 PM
Nanotechnology of Homeopathic Medicines leading to new manufacturing methods
Speaker: Jayesh Bellare Ph.D.
Presentation focus: Nano-medicines have gained prominence in recent years, but surprisingly nano-medicines are ubiquitous across multiple systems of medicine, particularly in Homeopathic medicines. Today, nanomedicines have proven their advantages in many modern medicinal molecules, where they show significantly improved performance. Our work has demonstrated that Homeopathic remedies have nanoparticles in them. Nanoparticles show improved biological activity. In Homeopathic medicines, a controversy has existed regarding the extremely high dilutions used (one part in 10 raised to 400 parts is typical) during manufacture, which goes against Avogadro’s number and the molecular basis of matter. This rules out the possibility of the presence of any starting material of the medicine in the highly diluted finished product. Because of this, the molecular basis of the medicinal action of the drug was always in doubt. Using electron microscopy, we showed for the first time that nanocrystals of the starting materials are present in the final product despite the extremely high dilutions. The process of manufacture and equipment used in manufacture is important to produce the effects seen. By understanding the process of manufacture, and probing them with tools of nanotechnology, and modern science like particle velocimetry, we show how these nanoparticles arise and persist in the medicine through froth flotation. Silicate chemistry plays a key role in coating and retaining the starting material in the solution. TEM images show core-shell morphology, consisting of inorganic salt core surrounded by sodium silicate, which caps and stabilizes these particles. We explain origin and mechanism of silicate coating during manufacture. Selected area electron diffraction (SAED) and energy dispersive analysis (EDS) show patterns consistent with the relevant inorganic salt and simultaneous presence of meso-microporous silicate around it. Biological experiments with cell lines show that there is a biological effect at rather low concentrations of the substances, consistent with a so-called hormetic effect. Based on this work, a novel route of potentization is proposed by restricting dilutions to below Avogadro’s limit while maintaining sufficient number of succussions for ensuring the efficacy of drugs. This novel route ensures presence of measurable/detectable starting material in final products, as validated here by High-resolution transmission electron microscope (HR-TEM and its various modes) and inductively coupled plasma-mass spectrometry (ICP-MS). This innovative approach to potentization will aid in accurately labelling the establishing the ingredients and composition of homeopathic medicines.
Characterization of the material and electrodynamic aspect of high Homeopathic potencies
Speaker: Michel Van Wassenhoven MD, Coordinator of DynHom Research Project, Chastre, Belgium
Presentation focus: The focus of DynHom (DYNamisation HOMeopathy) project, launched in 2014, is to study the physicochemical properties of homeopathic medicines, especially in high dilutions, and to characterize the effect of dynamization during the manufacturing process.
A wide range of analytical methods were used to determine the nature of homeopathic dilutions (NTA, freeze-drying), their molecular structure (NMR), chemical composition (HPLC, FTIR), appearance (SEM-EDX, EPA) and electrical (pH) properties. Various remedies (soluble, insoluble) were prepared according to the European Pharmacopoeia (dynamization), whith or without dynamization (simple dilution) and compared to their respective control (ethanol, lactose, water) prepared under the same conditions. The impact of the container (glass, PET) was also evaluated.
All these techniques have allowed us to show that: a) homeopathic dilutions are not simply water solutions; b) dynamization is not a simple dilution, c) a homeopathic preparation made from one raw material can be distinguished from another, even at the highest levels of dynamisation, and d) the highest dynamizations still contain matter which does not correspond to the initial stock, but all homeopathic medicines are made up of the same molecules, in proportions specific to the raw material. The main component for preparation in glass containers is sodium bicarbonate, followed by carbonates, alkanes and some silicates; in polyethylene containers silicates predominate. All these compounds generate electric fields. These molecules thus become carriers of electrical information or specific water polarization (morphogenic water).
In conclusion, thanks to various techniques, we can observe the different elements that make up homeopathic medicine. These are structured in a specific way for each remedy, which will have a specific potential for action. The key words to remember are the particulate and molecular structure of homeopathic solutions, which become polarized systems with the potential to regulate dysfunctional genes in living beings.
Conventional versus Homeopathic Treatment of Acute Injuries: Different Paradigms, Different Results
Saturday, October 18 / 4:20 PM – 5:15 PM
Speaker: Ronald D. Whitmont MD
Presentation focus: Homeopathic treatment has withstood the test of time and is ultimately supported by microbiome science. Conventional interventions are based on theories of opposition, are beholden to pharmaceutical industrial influences, and ultimately worsen and prolong injury, pain, and inflammation. This presentation will contrast the evidence-base of conventional Standard of Care medical practices (including the use of RICE protocols, NSAIDs, Steroids, Antibiotics, Opioids), their short-term benefits, and long-term risks, with homeopathic treatment (including individualization, pro-inflammatory, and microbiome compatible practices) that demonstrate both short, and long-term benefits.
Homeopathy’s contributions to modern clinical trials and practice: keys from the past and to the future
Saturday, October 18 / 5:15 PM – 6:00 PM
Speaker: Paul Herscu ND
Presentation focus: This discussion explores some contributions homeopathy has made to drug/clinical trials over the past two centuries that aided in modernizing them to their current state. Specifically, we highlight key insights that led to modern drug/clinical trial design. We then discuss how further changes could lead to fewer failed drug trials and refinements to current medical practice.
Homeopathy vs. conventional primary care in children during the first 24 months of life-a pragmatic randomised controlled trial
Saturday, October 18 / 6:00 PM – 6:45 PM
Speaker: Dr. Menachem Oberbaum MD
Presentation focus:
Background: This pragmatic, randomized, parallel-group, comparative trial was conducted at Jeeyar Integrated Medical Services (JIMS) Hospital, Telangana, India—a tertiary care center providing integrated primary care through homeopathy, Ayurveda, and conventional medicine. Newborns were randomly assigned to receive treatment for any acute condition with either conventional medicine or homeopathy during their first 24 months of life. Standard medical interventions were permitted in the homeopathy group only in cases of life-threatening emergencies. This pilot study aimed to compare these two treatment approaches by monitoring the incidence of illness during the first two years of life.
Methods and results: Of the 108 neonates enrolled, 99 (49 in the homeopathy group and 50 in the conventional group) were randomized to homeopathic or conventional care. The primary outcomes were the number of sickness episodes and sick days over the 24-month period. Secondary outcomes included the incidence of respiratory and gastrointestinal diseases, anthropometric measures (height and weight), emotional development, antibiotic use, treatment costs, and mortality.
Children in the homeopathy group experienced significantly fewer sick days (OR: 0.37; 95% CI: 0.24–0.58; p < 0.001) and fewer sickness episodes (OR: 0.53; 95% CI: 0.32–0.87; p = 0.013) compared to those in the conventional group. They also had fewer respiratory illnesses over the study period. Height gain was significantly greater in the homeopathy group (F(1, 97) = 8.92; p = 0.004; partial η² = 0.084), whereas weight gain did not differ between groups. The homeopathy group required fewer antibiotics, and their overall treatment costs were lower. Emotional development was comparable between groups.
Conclusions: In this small, exploratory trial, homeopathy was more effective than conventional treatment in reducing sick days, sickness episodes, and respiratory illnesses during the first two years of life. It was associated with reduced antibiotic use and lower overall treatment costs. These findings suggest that homeopathy may serve as a valuable adjunct to conventional medicine in early childhood, contributing to reduced morbidity and healthcare burden. A larger, definitive trial is proposed.
To our knowledge, no previous trials have directly compared homeopathy and conventional medicine as treatment systems rather than as therapies for specific indications. This study design overcomes the “one size fits all” design inherent in RCTs.
Addendum: This research was published in the European Journal of Pediatrics in November 2024. In February, 2025, with no previous notice, the journal notified the authors of its intention to retract the paper. The authors were easily able to rebuff all substantiative claims made against our work, none of which meet internationally accepted criteria for manuscript retraction. As of this writing, the authors await the final editorial decision.
Homeopathy Utilization Around the World
Sunday, October 19 / 9:00 AM – 9:45 AM
Speaker: Dr. Lee Kayne, Ph.D President of the Faculty of Homeopathy
Presentation focus: Homeopathy as a system of medicine has been established over 200 years and has an estimated global reach of over 1.4 billion people who have used it during their lifetime.
That it retains such acceptance and popularity in the face of often vociferous scepticism is remarkable and this presentation will explore some of the reasons behind that in terms of homeopathy’s cultural significance, popularity and practice in different countries around the world.
Examples from practice in select countries will illustrate the many different ways that homeopathy is integrated into medical practice and how this is shaped by major factors such as the regulation frameworks and education opportunities.
This presentation aims to provide a global overview of homeopathic practice, offering insights into its popularity and enduring relevance in today’s healthcare landscape, despite increased scrutiny driven by the desire for evidence-based healthcare. And asks what exactly constitutes evidence anyway?
Exploring the Molecular Evidences for Pre-clinical Research in Homoeopathy with Global Health Implications
Sunday, October 19 / 9:45 AM – 10:30 AM
Speaker: Shailendra K Saxena, PhD
Presentation focus: Homeopathy, distinguished by its unique principles, individualized approach, and distinct methodologies, fundamentally differs from conventional medicine in remedy preparation, patient evaluation, and therapeutic aims. Traditionally, homeopathic research concentrated on clinical verification and provings in healthy individuals; however, over the past two decades, there has been a significant shift towards investigating the biological activity of homeopathic remedies at the pre-clinical level. Advances in molecular biology and biomedical research technologies have opened new avenues for exploring the pharmacological and therapeutic effects of high-dilution preparations. Contemporary pre-clinical studies employ cutting-edge molecular tools such as gene expression analysis, proteomics, and cellular assays to elucidate potential mechanisms of action. Among the notable contributions is the pioneering research led by our team at King George’s Medical University (KGMU), India, which demonstrated that homeopathic remedies exert measurable antiviral effects against Japanese encephalitis virus (JEV). Utilizing advanced molecular techniques such as Next-Generation Sequencing, High-Throughput RNA sequencing, gene expression profiling, cytokine assays, and indirect- immunoflorescence evaluation etc, our findings provided compelling evidence that these ultra-diluted remedies can modulate host immune responses and significantly reduce viral load, thereby establishing biological plausibility. More broadly, our growing body of pre-clinical research integrates sophisticated molecular biology methods to reveal therapeutic effects of homeopathic medicines across various disease models. As biomedical science advances into the genomic and molecular era, emphasizing precision and personalized medicine, generating rigorous, reproducible pre-clinical evidence is essential to strengthen the scientific foundation of homeopathy. Such integrative research efforts will support the credibility, acceptance, and global integration of homeopathy into mainstream healthcare systems, ultimately enhancing its contribution to global health.
The Integration of Homeopathy and Complementary Medicines in the Public Health Service of the Tuscany Region (Italy): a successful experience
Sunday, October 19 / 10:50 AM – 11:35 AM
Speaker: Elio Rossi MD
Presentation focus: Complementary Medicine (CM) is being increasingly used by European citizens in order to increase their overall state of health and well-being, as well as to treat various illnesses and diseases. The interest for these therapies has progressively risen also in Italy and in Tuscany as well. In response to the increasing demand in the past few years by the Tuscan citizens, the region of Tuscany has started their integration in the healthcare service. Since 1996, the Tuscan Regional Healthcare Plans (RHPs) have been considering the role of Complementary Medicine (homeopathy, acupuncture, herbal medicine).
Aim. The aim of this presentation is to describe the pathway and results of the integration process of CM including homeopathy in the public healthcare service in the region of Tuscany (Italy) lasting more than 25 years.
Methods. The RHPs of Tuscany have started to incorporate several types of CM treatments (i.e., acupuncture, herbal medicine and homeopathy) in 1996.
Results. This represents the highest degree of integration of such therapies in the Public Healthcare system in Italy. Furthermore, the Region of Tuscany decided to include CM in the Essential Levels of Assistance (ELA/LEA) in 2005. Accordingly, a network of 84 public clinics providing CM health services was built (updated to December 2024) and the relative regulations (i.e., laws, bills, resolutions, etc.) were approved by the regional authorities. Moreover, the regional law for doctors and dentists, veterinarians and pharmacists, approved in 2007, became the basis on which the National State-Regions Agreement defining the modalities of professional training in homeopathy, acupuncture, phytotherapy was built. Finally, the Tuscany region has identified oncology and cancer care as a priority sector for complementary integrative medicine (CIM). In agreement with the Regional Institute for Study, Prevention and Oncological Network (ISPRO), some complementary therapies, including homeopathy, proven to be safe and effective were included in oncology protocols. In 2021 the Diagnostic, therapeutic and care pathways “Integrative medicine for cancer patients” was approved. It stated that patients with cancer can be treated with homeopathy, acupuncture and TCM, herbal medicine at every stage of their disease and in any type of cancer, to alleviate the side effects of therapies and the symptoms related to the disease and to improve the quality of life.
Conclusions. The Tuscan experience has shown the feasibility of CM integration into the Public Healthcare Service. This innovative process, which is characterized by an inclusive, modern and sustainable approach to the healthcare, might pave the way for a platform aiming to build integrated Healthcare Systems at a national and European level.
How Homeopathy Can Impact One Health and the Sustainable Development Goals of the U.N.
Saturday, October 18 / 11:35 AM – 1:20 PM
Speaker: Leoni Bonamin DVM, MSc, PhD.
Presentation focus: Environmental issues and the need to mitigate anthropogenic actions are urgent. Following the UN’s proposal to establish the 17 Sustainable Development Goals (SDGs), a natural movement emerged to search the scientific literature for articles related to the benefits of using homeopathy for the environment. Several examples fulfill at least eight of the 17 SDGs. The step forward was the emergence of new research articles highlighting the benefits of using homeopathy in crop production, animal husbandry, and environmental restoration initiatives, including the elucidation of specific mechanisms from basic research endeavors. The use of isotherapeutics is a common practice in treating chronic intoxications to minimize symptoms and facilitate the clearance of the toxic substance from the body. Artemia spp. is an aquatic experimental model for ecotoxicological trials; their embryonic ability to enter diapause when exposed to harmful environments is a promising model for understanding bio-resilience processes that follow isotherapeutic treatment of living systems after exposure to glyphosate, mercury chloride, and cyanotoxins. The results suggest facilitation of inducing diapause and expressing HSPs (heat shock proteins) genes. Additional results were obtained by controlling Cyanobacteria growth with different homeopathic potencies in vitro, and the possibility of tracking homeopathic electrodynamic signals using the method of solvatochromic dyes in lakes and watercourses under field or wild conditions.
Autoimmunity and homeopathy
Sunday, October 19 / 1:20 PM – 2:05 PM
Speaker: Denise Straiges, MA, RSHom(NA)
Presentation focus: One in ten people in the world has been diagnosed with an autoimmune disease. In the US, the Autoimmune Registry estimates that there are more than 150 diseases—affecting up to 30 million people—that are autoimmune in origin. Most troubling is that these serious chronic diseases are now being diagnosed in children. “New” conditions such as PANS/PANDAS (Pediatric Acute-onset Neuropsychiatric Syndrome/Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections) demonstrate how acute infectious diseases are exploding into serious, debilitating autoimmunity.
What’s the thru line?
Autoimmunity is rapidly evolving relative to the human inability to adapt to our environment. The bio-reductionistic paradigm that has dominated medicine, public health, and hygiene since the close of the 19th century has effectively, through its anthropocentricity, failed to acknowledge the interdependency of humans with the smallest micro-organism, plants and animals, as well as the food and water supplies, resulting in a disrupted ecosystem around us—and within us.
Homeopathy is based on universal laws that don’t change—despite scientific “progress” or alterations to human circumstance. This talk positions Homeopathy as the bridge between the Hippocratic roots of healing and the biomedical paradigm of 21st century and provides clinical cases to underscore the capacity of this elegant system to unravel even the most complicated cases of autoimmunity.
Epidemic Preparedness – A Possible Role for Homeopathy
Sunday, October 19 / 2:05 PM – 3:00 PM
Speakers: Wayne Jonas, MD and John Ives, Ph.D.
Presentation focus: Nosodes, which are homeopathic preparations of potent infectious material, have been used to treat and prevent infectious disease for centuries. However, little rigorous research has been done to try and validate these claims, and even less on the underlining mechanisms of these preparations. In this session we present a series of studies both clinical as well as in the laboratory, examining the use of a COVID nosode for the prevention of COVID infection. We will also discuss the discovery of nanoparticles apparently generated from the infectious material during the preparation process, and which appear to be the active agents. Further research in this area has implications for controlling epidemics and pandemics in the future.”
BiosimCovex (Nosode) against COVID-19: Emerging Directions in Nanoprophylaxis
Speaker: Rajesh Shah, MD
Presentation focus: BiosimCovex, a novel nosode-based nano-prophylactic, was developed during the COVID-19 pandemic, standardized, and evaluated through animal toxicity studies, Phase 1 and Phase 2 (feasibility) trials, drug-proving studies, and basic nanoparticle characterization assays. Phase 1 and 2 clinical trials, together with drug-proving, established its safety, efficacy, immunomodulatory effects, and provided evidence of antibody formation. A Phase 2 feasibility trial involving 2,233 high-risk participants demonstrated reduced infection rates, a shorter disease course, and decreased hospitalization. Further expansion into Phase 2/3 multi-site studies across 14 Indian centers confirmed prevention of infection, highlighted by the breakthrough finding of COVID-19-specific antibody formation, which the co-authors will present. With reproducibility, safety, and multi-institutional validation, BiosimCovex emerges as a promising new category of nano-prophylaxis for preventing infections. This is the first-of-its-kind human study demonstrating not only the efficacy of nosodes in a pandemic but also that a homeopathic medicine can trigger antibody generation, encouraging further research.